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Genetics of different psoriatic manifestations

Psoriasis is a chronic inflammatory skin disorder that belongs to the auto-inflammatory diseases. Clinically, psoriasis is characterized by various manifestations. The most common forms are  psoriasis vulgaris (also known as plaque psoriasis), prevalent in 2-4% of northern European, as well as psoriasis-arthritis, diagnosed in 20-30% of psoriasis vulgaris patients due to a certain involvement of joints. In addition, there are several other seltenere Formen rarer psoriatic manifestations, such as generalized pustular psoriasis, SAPHO syndrome and palmoplantar pustular psoriasis, which differ clinically and genetically.